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Cake day: April 12th, 2025

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  • There are other options and substitutes, known as chemically defined media(CDM), because ultimately FBS is just a chemical slurry that can be replicated via any other ingredients like Gatorade.

    The reason FBS is used extensively is because of the long history of it’s use and when trying to do something new limiting variables is critical. It’s an issue of there needing to be a new standard, but that one XKCD mentality is preventing it.

    The two major drawback of FBS is that, ironically, it’s a biological product and the composition can vary wildly between batches, and that it’s stupidily expensive at ~$1500 USD per liter. You will not be purchasing a lab grown burger made with FBS unless you have thousands of dollars to spend per burger.

    However, without oversight, certification programs and forced transparency it can be expected that these companies are going to cut corners, but it’s going to be via other low cost animal product additives like gelatin, eggs, chitin etc.